The journey for a drug from invention to market is a long one. It has been estimated that the time required to develop a new drug de novo ranges between 10 and 17 years; that is, if it ever makes it. The chance for a new drug to actually make it to market is only 1:5,000. These slim chances are accompanied by the high cost for developing a new drug, which may reach an average of US$ 403 million. These rising costs threaten to make the development of new drugs increasingly unaffordable for both companies and patients.